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Stem Cell Research Free Write
In todays world of medicine, stem cell research is considered to be the most modern of all forthcoming forms of therapy, when in fact it is not. Stem cells were discovered in 1961 by Dr. James Till and Ernest McCulloch who both worked at the Ontario cancer institute at the time. The existence of stem cells and their ability to essentially transform into any other type of cell in the human body was an incredible first step in the long since developed and debated topic of stem cell therapy. Stem cells were immediately suggested as a cure all for diseases originally thought to be incurable and chronic illness; none more notorious than Cancer. Since
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Embryonic Stem Cell Research
Almost everyone in the world knows someone who has suffered because of disease. All people whose lives have been devastated by disease have asked or hoped for a cure. What everyone should know is that a cure is possible, but some beliefs are stopping cures from being found. Embryonic stem cell research could provide solutions to medical illnesses that scientists and doctors have been searching for for years. However, certain belief systems argue that an embryo is a person, and destroying an embryo for research is murder. The essential question concerning stem cell research is summed up by this quote from President Bush, “"As I thought through this issue I
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Stem cells have offered much hope by promising to greatly extend the numbers and range of patients who could benefit from transplants, and to provide cell replacement therapy to treat debilitating diseases such as diabetes, Parkinson's and Huntington's disease. The issue of stem cell research is politically charged, prompting biologists to begin engaging in ethical debates, Stem cell research offers great promise for understanding basic mechanisms of human development and differentiation, as well as the hope for new treatments. However, human stem cell research also raises sharp ethical and political controversies. This paper will discuss the types of stem cells as well as some of
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Stem Cell Research
Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.
Different types of stem cells
Embryonic stem cells - These stem cells come from embryos that are three to five days old. At this stage, an embryo is called
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Human embryonic stem cells (hES cells) are currently discussed not only by the biologists by whom they were discovered but also by the medical profession, media, ethicists, governments and politicians. There are several reasons for this. On the one hand, these ‘super cells’ have a major clinical potential in tissue repair, with their proponents believing that they represent the future relief or cure of a wide range of common disabilities; replacement of defective cells in a patient by transplantation of hES cell‐derived equivalents would restore normal function. On the other hand, the use of hES cells is highly controversial because they are derived from human pre
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reconstituted zygote is activated. The reconstituted zygote has the potential to divide into a blastocyst, and if implanted, develop into a child genetically identical to the nuclear donor. There are two fundamentally distinct types of human cloning by somatic cell nuclear transfer: reproductive cloning and therapeutic cloning. The objective of reproductive cloning is to produce a child genetically identical to an individual. This has been suggested as a last resort when an infertile couple are unable to conceive a biologically related child via any other method (Zavos, 2001). The objective of therapeutic cloning is to produce embryonic stem cells that are genetically identical to a patient
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Main Types of Tissues
1. meristematic tissue
- new tissue is produced through mitosis
- present in all vascular plants
- present in difference regions of a plant
- embryonic tissue
- make up "meristems"- areas of rapidly dividing cells
- as they mature, meristematic cells specialize into other cell types
- primary growth (tall)
- apical meristem - tips of stems & roots
- intercalary meristem - stems and @ base of leaf blades
- secondary growth (fat)
- lateral maeristem - increase in root & stem circumference;
adds vascular tissue, strengthens stems, support for plant as it grows
- vascular combium- thin layer length of root & stem: new
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14. Liver stem cell niche 17
15. Conclusion 18
16. Abbreviations 19
17. References 20
The liver is found in all vertebrates, and is typically the largest visceral organ. Its form varies considerably in different species, and is
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* Transgenic Organism – when a plant cell is inserted into an animal cell and vice versa. The foreign gene will behave the same way as it would in its own species
* Genetic fingerprinting – using someone else’s DNA to establish their identity and is useful to confirm the pedigree of valuable species and checking the population of a species
* Specialised cells – cells that can only do certain jobs and can only use a small amount of their DNA
* Stem cells – are not specialised and can take on any role
* Mitosis – process of when a cell divides into two daughter cells, each with the same number of chromosomes as the original cell
* Meiosis – organisms that reproduce sexually and
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neurons in that region through synaptogenesis. Neurons fight for synaptic sites and a chemical the target site releases. Neurons that make adequate connections and receive enough of that chemical will live, and those that don’t will die. This is called cell death or apoptosis. After cell death many synapse are lost or many more are formed, this process is called reorganization. One type of cell in the brain is stem cells that can develop into any cell type. Another type of cell is the radial or glial cell which are small and provide a guide for migration and provide support functions to the brain. There are four types of glia cells. Swann cells and Oligodendrocytes wrap around axons and provide
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waste and maintain an ionic balance of fluids? | |segment, the solid waste | | | |
| | |exits through the anus | | | |
|Growth and Development |start out as a small cell|Starts out as fertilized | | | |
|Does the organism go through metamorphosis, develop in an egg or
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bacteria are so called because they take up the violet stain used in the Gram staining method. Gram-positive bacteria are able to retain the crystal violet stain due to their thick peptidoglycan layer in their cell wall. This layer is superficial to the cell membrane. Cell walls provide structural support, protection and rigidity to the cell.
Importance of Gram-Negative
- Gram-negative bacteria are at the root of about 30% of the hospital-acquired infections in the U.S., researchers said. Although they don't account for the majority of these types of infections, they have "features that are of particular concern," including highly efficient ways of gearing up for drug resistance and a
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analysis and function, as well as gene structure and function in greater depth. In our final year we were introduced to pathology of diseases, and the use of biochemistry in research, diagnosis and treatment.
Although the topic of cancer had been briefly exemplified in previous years, the Advanced Biochemistry and Advanced Biochemistry of Cancer modules provided me with more in depth knowledge on key topics. Advanced Biochemistry of cancer focused on the nature and function of oncogenes and tumour suppressor genes in normal and cancer cells, transformation of a normal cell to a cancer cell, and its progression to tumour formation and metastasis. The module also touched on the role of stem
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Banana Fiber Textile Products -----Fruit Clothing,Love Life,Love Earth |
| Banana fibers such as flax, jute, hemp, and pineapple etc plant fibers. are all made up of thick walled cell tissue and they are bonded together by natural gums and support the branches, stems, leaves and fruits. Although banana plants and fibers are available in tropical regions in abundance, their application potential has not been exploited fully. At present,other companys make the limited application of banana fiber ,for example, in making ropes, mats, and some other fields such as the composite materials. In recent years, more and more plant fibers were considered to be "environmentally friendly
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Cell body lies in a nucleus of the brain stem or spinal cord
Triggers a contraction in innervated muscle
Only axon of lower motor neuron extends outside CNS
Destruction of or damage to lower motor neuron eliminates voluntary and reflex control over innervated motor unit
15-5 Somatic Motor Pathways
Conscious and Subconscious Motor Commands
Control skeletal muscles by traveling over three integrated motor pathways
15-5 Somatic Motor Pathways
The Corticospinal Pathway
Sometimes called the pyramidal system
Provides voluntary control over skeletal
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are also more personalised and promote regeneration of the organism.
Clearly, as areas of research such as biomaterials or tissue engineering are developed for use in regenerative medicine, the range of opportunities will increase dramatically. Josep Anton Planell, the director of the Institute for Bioengineering of Catalonia (IBEC), which was formed by the UB, the UPC and the Generalitat (Government of Catalonia) and has its headquarters in Barcelona Science Park, considers that “in the future, it will be possible to design intelligent biomaterials that, when placed where damaged tissue needs to be regenerated, will be able to stimulate the stem cells to do what we want them to do
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13. Genetic determinism is the idea that our genes control everything about us, with little or no outside influences.
The Body: Cells, Tissues, and Organs
1. The human body is composed of about 37 trillion cells. All cell types except mature red blood cells contain the entire genome.
2. Differential gene expression creates more than 290 distinctive cell types, which combine to form four basic tissue types that interact to form organs and organ systems.
3. Many organs contain stem cells that “self-renew” as well as produce cells that specialize. These two properties are essential for growth, development, and healing.
Relationships: From Individuals to Families
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. Spinal tap (lumbar puncture). The definitive diagnosis of meningitis requires an analysis of your cerebrospinal fluid (CSF), which is collected during a procedure known as a spinal tap. In people with meningitis, the CSF fluid often shows a low sugar (glucose) level along with an increased white blood cell count and increased protein. CSF analysis may also help your doctor identify the exact bacterium that causing meningitis.
2. Memory: repeating statements and questions over and over, not realizing that they’ve asked the question before. Forget conversations, appointments or events, and not remember them later. Routinely misplace possessions, often putting them in illogical locations
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for Latinos could be twofold: one is religious affiliation, and two, commitment to a cause. With this idea comes two thoughts, in other words, the more connected a person believes his or herself to be to a community the more apt they are to engage themselves toward a particular cause. To further explore these ideas, we will look at the fall 2008 Presidential Election, according to the U.S. Census Bureau the fall 2008 Presidential Election was the most diverse in history. Latinos came to the polls unified by religious factors in relation to “moral issues” such as same-sex marriage, stem cell research, and abortion.” (U.S. Census Bureau election results) These are all issues supported by the
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fingers represent the _____; the palm of the hand represents the _____; and the forearm represents the _____. |
| Student Answer: | | dendrites; myelin, axon terminal |
| | | somas; cell body; dendrite |
| | | receivers; generator; transmitter |
| | | dendrites; cell body; axon |
| Instructor Explanation: | See Chapter 2, p. 37 - 38 |
| Points Received: | 2 of 2 |
| Comments: | |
19. | Question : | (TCO 3) What is the part of the neuron that performs cleanup tasks and insulates one neuron from another so that neural messages do not get "scrambled?" |
| Student Answer: | | soma |
| | | dendrites |
| | | axons
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) is the most severe childhood retinal dystrophy, characterized by a non detectable electroretinogram (ERG) and other symptoms soon after birth. There is no straight forward way to correct the inherited defect in retinal dystrophies as can be done, for example, for the anterior segment disease, were a relatively simple operation can substantially improve vision. There are several possible therapeutic strategies currently be evaluated for diseases of retina, including pharmacological intervention, retinol transplantation, stem cell-based approaches, and gene therapy.
* Respond to each of the following questions:
What is an abstract? How is an abstract helpful in
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of chanting has to be carried out each day until the patient is completely healed. Although this process is not scientifically proven to be true, Dr. Masaru Emoto who wrote ‘The hidden Messages of water’, has proven that sound changes the molecular structure of body. And since our body consists of over 75% water, sound of prayers and chanting may create change in the body. Chanting techniques helps vibrate different areas of the body through certain words, vowels and mantras.Dr. Doris Taylor who is a stem cell researcher specializing in cardiac medicine at the University of Minnesota said the power of the mind in relation to illness and healing is a part of the future of medicine and that
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Centre for Stem Cell & Tissue M.Sc. (2 years Course) Engg. Community Education & Disability B.Ed.Special Education Studies specialization in learning Disability
Gandhian and Peace Studies Geography
M.A. Gandhian and Peace Studies M.A. Geography M.A. Remote Sensing & G.I.S. M.A. Disaster Management
29 51+7* 25+3 Sponsored by Govt./Institute 25+3 Sponsored by Govt./Institute 23 17 17 68
Indian Theatre Music
M.A. Indian Theatre M.A. Instrumental M.A. Vocal
Sanskrit School of Communication Studies
M.A. Sanskrit Postgraduate Diploma Courses in : Advt. and Public Relations Hindi Journalism Punjabi Journalism
15 15 15 30+4* 46&6*
M.A. Social Works
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grew the most nerve cells. This, too, might be BDNF at work, transforming stem cells into full-grown, functional neurons. "It was extremely exciting to see this exercise effect in humans for the first time," says Scott Small, a Columbia University Medical Center neurologist who coauthored the study with Salk Institute neurobiologist Fred Gage. "In terms of trying to understand what it means, the field is just exploding."
The first step toward that understanding is to figure out exactly where the new brain cells are growing--and whether that is a part of the brain that needs to be rejuvenated. In Small and Gage's experiment, the new neurons created by exercise cropped up in only one place: the
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dissatisfaction, but not act as actual motivators
Paying workers can act as enticement (i.e. “movement”), but movement is different from actual motivation which makes it necessary for motivators to exist
Motivators stem from job enrichment – through assigning complete units of work through teamworking or cell production, providing feedback on performance, and through job enlargement
2.5.3 – Apply the content theories of Mayo and McClelland.
* Mayo’s Hawthorne effect (for human relations psychology) proposed a series of conclusions:
Changes in working conditions/financial rewards had little effect on productivity
Management consulting and communicating with staff improved motivation
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cumbersome preparation procedures. Developing a preserved product from the banana blossom would eliminate such difficulties and offer benefits to the consumers such as prolonged shelf life, convenience in preparation as well as promoting the intake of fiber rich vegetables among people. This will also allow exploring more marketing niches in the western countries.
Banana, plantain or Musa paradisiaca is a large, herbaceous plant native to India and Southeast Asia. Purple buds appear from the heart of the tip of the stem and develop into tubular, white flowers. Along with dietary fibers, proteins and unsaturated fatty acids, banana flowers are also rich in vitamin E and
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inefficiencies, they are taking some steps to improve it. AT&T has created an iPhone application that allows users to report specific geographic areas with poor service. AT&T also spent over $17 billion in 2009 to double the capacity of its 3G network through software enhancements. They are also increasing the downlink capacity on their high-speed packet access (HSPA) from 3.6 megabits per second to 7.2 through software upgrades. In addition, AT&T is adding HSPA carriers at cell sites on a “market-by-market basis” and upgrading their backhaul network to handle the increased data traffic. All of these are legitimate steps to address customer concerns, but they may be too little too late. The AT
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NAME: IHEKANANDU KINGSLEY N.
COURSE: MGMT 292 / F12 N01
TITLE: INDIVIDUAL CASE STUDY (LAFARGE S.A.)
SUBMITTED: October 5, 2012
TABLE OF CONTENTS
2. INTRODUCTION 3
3. DESCRIPTION OF CASE 4
4. VALUES 4
4.1. Types of values 4
5. TEAMWORK 7
6. MOTIVATION 8
7. CREATIVITY 9
7.1. Components of creativity 9
8. CONCLUSION 12
9. BIBLIOGRAPHY 13
This report aims to provide an in-depth analysis of initiatives pursued by Lafarge as presented in the case study. The analysis is centered on four Organizational behaviour concepts which include Values, Teamwork, Motivation and Creativity.
The initiatives entail different strategies deployed by Lafarge in handling challenges encountered in
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Financial statements are the most common tool used for making business decisions. They consist of the balance sheet, income statement and statement of cash flows. The analysis tools used affect all aspects of a company not just a few.
A systematic review of the resources a company used to achieve its mission is cost control. Cash flow should be kept at necessary levels for operations is one of the major benefits of cost control. It is a very good thing when large amounts of cash are not tied up in too much inventory or high supply stocks and over staffed departments. Cash will now be available for other purposes such as navigating economic waves, expansions needs or equipment maintenance
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The period of time including and following Operation Blue star is considered a dark time in India and black spot in Indian history. It is a time Indian would rather forget, yet still to this day debate about. Was Indihar Gandhi correct in instating operation Blue Star, inflicting damage to the Golden temple, and being responsible for the killing of anywhere from 492 (official reports) to 1500 (estimates run as high as) civilians, which lead to an additional 5,000 Sikh deaths following, due to anti-Sikh riots? Was Indihar Gandhi’s actions justified, and could her problems with the Sikhs have been solved in any other way? These are all question India still debates to this day. We will look at
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There are many individuals in a child’s life that helps mold them into a well-rounded adult. In most cases, this guidance comes from the child’s parents or other older, but in Sonny’s case, this guidance was expected from his older brother. In the short narrative, Sonny’s Blues, Sonny’s life was adversely affected by the decisions that his older brother made. The decisions that his brother made include leaving Sonny to stay with his fiancée Isabel and her family while he was in the military as well as not accepting Sonny’s not accepting Sonny’s decision to become a musician.
While making his first steps, young Sonny ran and fell into the arms of his older brother
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Jail Responsibilities Monique Priorello
September 23, 2012
One of the main responsibilities of a jail is to give the officers the correct “Police Correspondence” courses. This is because these courses give the officers the effective basic training that they need to do things such as; Writing of Memoranda, Police Reports, and Civilian Letters. What needs to be done first is make sure that there are NO errors. This means in spelling, punctuation, price, and grammar. These should be thoroughly, and constantly, edited. Another thing is conciseness; this means it should be brief or limited in words. Although, concision does not mean deleting words that count just to make
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October 15, 2012
- 1 -
[no notes on this page]I. Job description
II. Job specifications
III. Form of departmentalization
Starbucks have been named in the 100 best companies to work for. Starbucks has many job
opportunities for people, which require the right job specifications. The employees create uplifting
experience for the people who visit the stores and make perfect beverages. Within this paper I will
- 2 -
[no notes on this page]discuss and answer the four questions asked from the case student in Chapter three about
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Fight Club is a story of the narrator’s struggle to gain control over his life. He is in search for an identity in the form of manhood. His masculinity is so repressed because of the absence of a father figure in his life. Because of this he creates Tyler, his alternate personality. Tyler is nothing like anyone the narrator has met, he is self assured and completely free. The narrators alternate personality Tyler Durden is the ultimate alpha-male. Tyler becomes the narrator’s hero and he envied him. After creating Tyler the narrator’s view on the world is adjusted. Tyler ends up changing the narrators life and has him doing things he never thought he would do.
Both the narrator and Tyler
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The Powers of the Health and Safety Representative
A health and safety representative has the power to:
Identify Workplace Hazards
The health and safety representative has the power to identify workplace hazards. This power is usually exercised by conducting workplace inspections.
Obtain Information from the Employer
The health and safety representative is entitled to the same information available to a joint committee member. Under the Act, the employer must share with the representative any such information that he or she has.
Be Consulted about Workplace Testing
If the employer intends to do testing of any kind in or about the workplace and related to occupational health and safety
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by Vivien Alcock
Table of Contents
About Short Stories
Beyond The Text
Panel of Writers
Welcome to the World of Literature and to Short Stories!
We hope you will enjoy working with this guidebook, which has been specially designed to help you prepare your students enjoy the Literature Component of the KBSM English Language syllabus.
A brief explanation of the short story genre has been provided together with suggested activities, teaching steps and worksheets/handouts. An answer key with suggested answers has been provided at the
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Coca-Cola Global Business and Marketing Strategy Introduction As domestic markets mature, it is becoming more and more fashionable for organisations to seek growth through opportunities in foreign countries. Faster communication, new technologies and improved transport links are making international markets more accessible and businesses pursuing a global position can experience an upsurge in brand awareness and cost effectiveness. Global marketing is a relatively new concept linked to these developments. In the main, it is concerned with decisions for integrating or standardizing marketing actions across a number of geographic markets. This does not rule out any customization of the
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Facing poverty with a rich girl’s habit
October 22, 2012
Facing poverty with a rich girl’s habit was written by Suki Kim and published in the New York Times on November 21, 2004. The most important point that Suki want to make was that (1) what we have in life can be taken away in an instant (2) do not go bankrupt in South Korea (3) that a person must adapt and endure through the trials and tribulations in their life and (4) that no matter what you have or don’t’ have in life you must always be true to yourself.
Some of the other main points in this story are that Suki’s father owned shipping, mining and hotel
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-4-50 paperLack of exercise is a key contributor to disease and death among many people in the United States, regardless of age. It is a well-known fact that exercise results in a healthier lifestyle. Along with tobacco use and poor nutrition, lack of exercise is one of the main issues that people have which leads to high blood pressure, obesity, and other serious health problems.
According to a study by UCSD School of Medicine and SDSU researchers, lack of physical activity is the main contributor to obesity in children from age 11 to 15 (10 News, 2004). That study showed that 45 percent of 878 children were either at risk for becoming overweight or were already classified as overweight
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Capitalism is an economic system in which private individuals and business firms carry out production and exchange of goods and services through complex transactions involved in prices and markets.
By extension called capitalist higher social class of this economic system ("bourgeoisie"), or to the common form would the individual interests of capital owners in both companies, shareholders and patterns, also called capitalism entire social and political order (law, idiosyncrasies, etc..) that orbits the system while structurally determines the possibilities of its content.
Capitalism is based ideologically in an economy in which the market prevails, it is usually given
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Homelessness in America
Homelessness in America is a social problem that we are faced with on a daily basis. Despite the vast number of research done by Americans on homelessness, little is still known about the effect that it has on our society. The overall image that emerges from the effects of homeless people is negative: they’re seen as lazy, drug users, alcoholics, and worthless. This study recovers some of the homelessness perspective for an American audience through research, data, and an interview by a homeless person living in Georgia. This study
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Community Volunteer Service Assignment
Why you chose this agency?
I chose this Sharing God’s Love, because I was interested in what kind of services they provide. I also wanted to know if there was any help out there for the people in need with mental illnesses. I also had lots of my kid’s old clothing that I needed to get rid of, so I donated it to them.
Describe the population the agency serves.
The population that the agency serves is those with financial difficulties. They may have lost their job or had an unexpected expense where their car needed repaired.
Identify the services provided by the agency. They rarely see the homeless population
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According to Department of Defense of the Unites States, May 21, 2007 the Deputy Secretary of Defense and Executive Agent for Space recognized the Operationally Responsive Space (ORS) Office as a practical step to adjust space competences to be altering national security necessities and to be an agent for transformation across the public. ("Operationally responsive space,”) The Operationally Responsive Space (ORS) is relatively a new office. According to Plan for Operationally Responsive Space, Operationally Responsive Space (ORS) is defined as guaranteed space power concentrated on time satisfaction of Joint Force Commanders’ needs. Its reflects ORS as a subdivision of space actions
1371 words - 6 pages
15.566 Information Technology
Calyx and Corolla Case Questions
Leslie Prince Rudolph
15.561A and 15.566
Example Case Writeup for
Calyx and Corolla
#1 – Value Added Chain
The value-added chain for typical florists can be depicted as follows:
call in order
The distributors are typically located in the growing regions. The wholesalers are
geographically dispersed. Most flowers are ordered directly from the florist and
delivered to the recipient (consumer). Small family-operated companies dominate the
entire chain. In many cases, industry participants have some role across the organizations
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Unfreeze, Change, Freeze
Kurt Lewin proposed a three stage theory of change commonly referred to as Unfreeze, Change, Freeze (or Refreeze). It is possible to take these stages to quite complicated levels but I don't believe this is necessary to be able to work with the theory. But be aware that the theory has been criticised for being too simplistic.
A lot has changed since the theory was originally presented in 1947, but the Kurt Lewin model is still extremely relevant. Many other more modern change models are actually based on the Kurt Lewin model. I'm going to head down a middle road and give you just enough information to make you dangerous...and perhaps a little more to whet your
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Personal Experience with Language
Language is a big part of my everyday life. I hear different languages being spoken in many places. I experience a different kind of language the most at the nail salon. Language has a big effect on everyone, in my opinion every time I walk into the nail salon I hear someone talking in a different kind of language. I have no idea what they are saying, but I find it very impressive that most of them can speak English and their language, Vietnamese.
As soon as I walk into the nail salon I always hear them talking to one another in their own language. I am sometimes very curious as to what they are saying. For example, they will carry on a conversation with
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In this report, we will discuss about the capital budgeting of CapitaLand, one of the largest real estate companies in Asia. Business activities and financial background of CapitaLand will be mentioned in this report, also with the evaluation of two potential mutually exclusive capital investments as well as the objective of these investments for this company.
This report also contents the analysis of four main different capital budgeting techniques used in the investments for supporting decision making process. Definition, formula of each technique will be given along with the figure of the investments as well as its advantages and disadvantages. The numeric data
1283 words - 6 pages
The Buffalo National River
The Buffalo National River begins as a trickle in the Boston Mountains, where it flows north and then eastward through the Ozark Mountains until it merges 150 miles later with the White River at Buffalo City.
The upper Buffalo offers the river’s finest scenic beauty. With its massive, towering bluffs, countless waterfalls, watchable wildlife, ties to both historic and prehistoric cultures, and remote, unspoiled location, the upper Buffalo National River wilderness is surely mid-America’s finest outdoor destination.
In fact, the entire river is such a special place that in 1972, Congress designated it as America’s first national river. This unique status
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1. According to the Statement of Cash Flows, Chesapeake has a positive cash flow from operations in the amount of $27.8 million in 2009. Moreover, there is a negative cash flow from investing and financing activities in the amounts of -$6.7 million and -$31.1 million, respectively. Chesapeake invested $6.7 million in fixed asset acquisitions. However, Chesapeake still has an overall positive cash flow in the amount of $27.2 million. Although this amount is $10 million lower than the last fiscal year (2008), this should not be too much of a concern at this time because $10 million was used to pay down long-term debt. Overall the main sources of cash was from operations and the main uses of